Correlation Between Sedation Depth Monitoring and Reflexes During Intravenous Anesthesia With Dexmedetomidine and Remifentanil in Children Undergoing Direct Laryngoscopy for Surgical Procedures

Launched by UNIVERSITY HOSPITAL, ANTWERP · Feb 7, 2018

Keywords

ClinConnect Summary

This clinical trial is looking at how well a special monitor, called the NeuroSENSE® NS 701 Monitor, can measure the depth of sedation in children while they are receiving anesthesia during a procedure called direct laryngoscopy. This procedure involves looking at the throat and airway, and it may require surgery. The study aims to see how the level of sedation relates to the child's reflexes during the anesthesia, using two medications: dexmedetomidine and remifentanil.

To participate in this trial, children aged between 30 days and 21 years who are scheduled for this procedure can be included if their parents or legal guardians give written consent. However, children cannot participate if they refuse consent, have allergies to the study medications, or have low oxygen levels before anesthesia. Families can expect to be part of an important study that aims to improve the safety and effectiveness of anesthesia in children.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • scheduled for elective direct laryngoscopy with surgical intervention, written informed consent of their parents or legal guardian.
• Exclusion Criteria:
• • refusal of informed consent, known allergy for dexmedetomidine or remifentanil at start of anesthesia pulse oxygen saturation (SaO2) lower than 85%