Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

Launched by OHIO STATE UNIVERSITY COMPREHENSIVE CANCER CENTER · Apr 2, 2018

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technique called confocal laser endomicroscopy (CLE) to help doctors diagnose pancreatic cystic lesions (PCLs) more accurately. The goal is to see if this advanced imaging method can provide useful information about the cysts before deciding if surgery is needed. Patients who are at least 18 years old and have a pancreatic cyst that is 2.0 cm or larger may be eligible to participate, especially if surgery is being considered.

If you join the trial, you will undergo a procedure known as endoscopic ultrasound (EUS) where doctors will use the CLE imaging to look at the cyst. They will also collect a sample of the cyst fluid for further testing. This trial aims to gather information that will assist doctors in making the best diagnosis and treatment decisions. It’s important to know that participation is voluntary, and you will need to give your consent before being enrolled. The findings from this study could potentially lead to better ways of diagnosing and treating pancreatic cysts in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient age 18 years or older
• • All patients referred for EUS-FNA of accessible PCL where surgery is contemplated
• • Minimum cyst size should be ≥ 2.0 cm as determined by prior cross-sectional imaging studies
• Exclusion Criteria:
• • Unable to obtain informed consent
• • Unable to tolerate the procedure
• • Women with known pregnancy at time of procedure
• • Patient age less than 18 years
• • Bleeding diathesis
• • Known allergy to fluorescein
• • Prior pancreatic cancer
• • Prior pancreatic surgery