Oxaloacetate Supplementation for Emotional PMS
Launched by TERRA BIOLOGICAL LLC · Apr 20, 2018
Trial Information
Current as of July 23, 2025
Completed
Keywords
ClinConnect Summary
Oxaloacetate is an energy metabolite found in every cell of the human body. It holds a key place in the Krebs Cycle within the mitochondria, providing energy to the cells. It is also a critical early metabolite in gluconeogenesis, which provides glucose for the heart and brain during times of low glucose. It is critical to human metabolism, proper cellular function and it is central to energy production and use in the body.
Oxaloacetate may affect Emotional PMS through multiple mechanisms. During PMS, there is a large increase in glucose utilization in the cerebellum of the brain in women ...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women with Emotional Premenstrual Syndrome (PMS),
- • Women who speak English as their primary language
- • Women who understand the Human Consent Form
- • Ability to swallow capsules
- Exclusion Criteria:
- • Formal diagnosis of clinical depression
- • Formal diagnosis of premenstrual dysphoric disorder (PMDD).
About Terra Biological Llc
Terra Biological LLC is a pioneering clinical trial sponsor dedicated to advancing innovative therapeutic solutions in the life sciences sector. With a focus on developing cutting-edge treatments, the company leverages a robust research framework and a team of experienced professionals to conduct rigorous clinical trials. Terra Biological LLC is committed to maintaining the highest standards of scientific integrity and regulatory compliance, ensuring that its studies contribute valuable insights to the medical community and enhance patient care. Through strategic partnerships and a patient-centric approach, Terra Biological LLC strives to address unmet medical needs and foster breakthroughs in drug development.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Lisa Tully, PhD
Study Director
Energy Medicine research Institute
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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