Personalized Treatment in Thyroid Disorders

Launched by JOHNS HOPKINS UNIVERSITY · Apr 23, 2018

Keywords

ClinConnect Summary

This clinical trial is studying a new device called the Collar Therapy Indicator (CoTI), which is designed to help measure how much radiation is absorbed by the thyroid gland in patients with thyroid disorders, such as thyroid cancer and Graves' disease. The CoTI looks like a turtleneck collar and continuously tracks radiation exposure, potentially providing more accurate information than traditional methods that only measure at specific times. Researchers believe that this could lead to better treatment plans and reduce the number of clinic visits needed for patients.

To participate in this trial, you need to be either diagnosed with Graves' disease or have a specific type of thyroid cancer that requires treatment with radioactive iodine. Participants should be able to understand and follow simple instructions in English. Throughout the study, patients will wear the CoTI device and share their experiences, including how comfortable it is and how easy it is to use. This trial aims to improve treatment outcomes and minimize side effects, such as low thyroid hormone levels after treatment. If you're interested, it could be a great opportunity to contribute to advancements in thyroid care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Group I
• • Patients with Graves' disease confirmed by laboratory testing.
• • Patients able to understand English and able to follow instructions. Group II
• • Patients with intermediate and high risk differentiated thyroid cancer requiring radioiodine remnant ablation or moderately high dose I-131 for treatment of residual cervical disease.
• • Persons able to understand simple English and able to follow instructions.
• Exclusion Criteria:
• • Patients with diseases involving cervical spine, such as spondylosis and severe degenerative joint disease.
• • Pregnant Women, elderly and persons unable to understand simple instructions