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Search / Trial NCT03533933

Clinical and Histomorphometric Analysis of Collagen Matrix Versus Connective Tissue Graft in Mucogingival Surgery in Orthodontic Patients

Launched by ELENA RUIZ DE GOPEGUI PALACIOS · May 21, 2018

Trial Information

Current as of July 07, 2025

Unknown status

Keywords

Collagen Matrix Connective Tissue Graft Histometry Xenograft Periodontal Regeneration Biometry

ClinConnect Summary

The purpose of this study is to confirm that periodontal regeneration happens after mucogingival surgery The principal outcome is compare the millimeters of new attachment create after a connective tissue graft and after the use of a porcine collagen matrix in teeth that have to been extracted (because of the orthodontic planing treatment) after mucogingival surgery .

The secondary outcomes are:

1. length of new cementum (histometry results)
2. length of the junctional epithelium (histometry results)
3. length of connective tissue attachment (histometry results)
4. complete root coverage ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patient in orthodontic treatment ,who needs mucogingival surgery in both hemi arcade and later the tooth adjacent to the graft should be extracted because of the orthodontic planing treatment .
  • The patient must be 18 years or older
  • Patient shows sufficient plaque control (FMPS \< 20%).
  • The patient is able to fully understand the nature of the proposed surgery and is able to provide a signed informed consent
  • Exclusion Criteria:
  • General contraindications for dental and/or surgical treatment are present.
  • The patient is taking medications or having treatments which have an effect on mucosal healing in general (e.g. steroids, large doses of anti-inflammatory drugs).
  • Untreated periodontal conditions
  • Patients not willing to participate

About Elena Ruiz De Gopegui Palacios

Elena Ruiz de Gopegui Palacios is a dedicated clinical trial sponsor with a strong commitment to advancing medical research and improving patient outcomes. With extensive experience in the design and management of clinical studies, she emphasizes rigorous methodology and ethical standards in all trials. Her leadership fosters collaboration among multidisciplinary teams, ensuring that each project is executed efficiently and effectively. Through her work, she aims to contribute to the development of innovative therapies and enhance the understanding of various medical conditions, ultimately striving to bring transformative solutions to the healthcare landscape.

Locations

Leioa, Biscay, Spain

Patients applied

0 patients applied

Trial Officials

Luis Antonio Aguirre Zorzano

Study Director

University of the Basque Country (UPV/EHU)

Elena Ruiz de Gopegui

Principal Investigator

University of the Basque Country (UPV/EHU)

Ana Maria Garcia de la Fuente

Principal Investigator

University of the Basque Country (UPV/EHU)

Ruth Estefania Fresco

Study Chair

University of the Basque Country (UPV/EHU)

Xavier Marichalar Mendia

Study Chair

University of the Basque Country (UPV/EHU)

Jose Manuel Aguirre Urizar

Study Chair

University of the Basque Country (UPV/EHU)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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