Clinical and Histomorphometric Analysis of Collagen Matrix Versus Connective Tissue Graft in Mucogingival Surgery in Orthodontic Patients
Launched by ELENA RUIZ DE GOPEGUI PALACIOS · May 21, 2018
Trial Information
Current as of July 07, 2025
Unknown status
Keywords
ClinConnect Summary
The purpose of this study is to confirm that periodontal regeneration happens after mucogingival surgery The principal outcome is compare the millimeters of new attachment create after a connective tissue graft and after the use of a porcine collagen matrix in teeth that have to been extracted (because of the orthodontic planing treatment) after mucogingival surgery .
The secondary outcomes are:
1. length of new cementum (histometry results)
2. length of the junctional epithelium (histometry results)
3. length of connective tissue attachment (histometry results)
4. complete root coverage ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patient in orthodontic treatment ,who needs mucogingival surgery in both hemi arcade and later the tooth adjacent to the graft should be extracted because of the orthodontic planing treatment .
- • The patient must be 18 years or older
- • Patient shows sufficient plaque control (FMPS \< 20%).
- • The patient is able to fully understand the nature of the proposed surgery and is able to provide a signed informed consent
- Exclusion Criteria:
- • General contraindications for dental and/or surgical treatment are present.
- • The patient is taking medications or having treatments which have an effect on mucosal healing in general (e.g. steroids, large doses of anti-inflammatory drugs).
- • Untreated periodontal conditions
- • Patients not willing to participate
About Elena Ruiz De Gopegui Palacios
Elena Ruiz de Gopegui Palacios is a dedicated clinical trial sponsor with a strong commitment to advancing medical research and improving patient outcomes. With extensive experience in the design and management of clinical studies, she emphasizes rigorous methodology and ethical standards in all trials. Her leadership fosters collaboration among multidisciplinary teams, ensuring that each project is executed efficiently and effectively. Through her work, she aims to contribute to the development of innovative therapies and enhance the understanding of various medical conditions, ultimately striving to bring transformative solutions to the healthcare landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Leioa, Biscay, Spain
Patients applied
Trial Officials
Luis Antonio Aguirre Zorzano
Study Director
University of the Basque Country (UPV/EHU)
Elena Ruiz de Gopegui
Principal Investigator
University of the Basque Country (UPV/EHU)
Ana Maria Garcia de la Fuente
Principal Investigator
University of the Basque Country (UPV/EHU)
Ruth Estefania Fresco
Study Chair
University of the Basque Country (UPV/EHU)
Xavier Marichalar Mendia
Study Chair
University of the Basque Country (UPV/EHU)
Jose Manuel Aguirre Urizar
Study Chair
University of the Basque Country (UPV/EHU)
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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