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Search / Trial NCT03541265

Liposomal Bupivacaine in Total Knee Arthroplasty

Launched by BRONX-LEBANON HOSPITAL CENTER HEALTH CARE SYSTEM · May 17, 2018

Trial Information

Current as of August 02, 2025

Completed

Keywords

Liposomal Bupivacaine Total Knee Arthroplasty

ClinConnect Summary

Multimodal pain approach is now an accepted standard of care to improve pain, enable earlier mobilization and faster recovery, decreased length of stay, and reduce opioid consumption and related side effects. The multimodal approach includes peri-operative oral and IV analgesics, local periarticular injections (PAI), and/or regional blocks such as femoral nerve blocks nerve or subsartorial saphenous nerve (adductor canal) blocks. Extended release bupivacaine (Exparel - Pacira Pharmaceuticals, Parsippany, NJ, USA) in liposomal form was developed for longer lasting post-operative analgesia. T...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • primary knee osteoarthritis undergoing unilateral knee replacement
  • Exclusion Criteria:
  • hypersensitivity and/or allergies to local anesthetics or previous knee surgery

About Bronx Lebanon Hospital Center Health Care System

Bronx-Lebanon Hospital Center Health Care System is a leading healthcare institution dedicated to providing high-quality medical services and advancing clinical research. Located in the Bronx, New York, the hospital is committed to improving patient outcomes through innovative treatment approaches and rigorous clinical trials. With a focus on diverse communities, Bronx-Lebanon engages in a wide range of research initiatives aimed at addressing health disparities and enhancing the understanding of various medical conditions. The institution's collaborative environment fosters partnerships among healthcare professionals, researchers, and patients, ensuring that clinical trials are conducted with the utmost integrity and adherence to ethical standards.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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