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Search / Trial NCT03553966

Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition

Launched by DR. KURT WOLFF GMBH & CO. KG · May 30, 2018

Trial Information

Current as of September 12, 2025

Completed

Keywords

Dental Caries Toothpaste Fluoride Hydroxyapatite

ClinConnect Summary

According to the criteria of evidence based medicine the use of fluoridated tooth paste (as well as fluoridated mouth rinses) with the exception of dietary control, are the only proven measures for the prevention of dental caries. Regular tooth brushing with a fluoridated toothpaste represents the golden standard of oral care also in the primary dentition established by numerous clinical studies.

Fluorides are widely used for caries prevention. However, particularly in children and adolescents the dosage of fluorides in oral care products must be carefully monitored, as chronic overdosing ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age 3-6 years
  • complete set of fully erupted primary molars (teeth 55, 54, 64, 65, 75, 74, 84, 85)
  • presence of a caries restoration (filling) on a minimum of 1 primary molar
  • minimum of 4 primary molars without a restoration or fissure sealing
  • Exclusion Criteria:
  • untreated caries lesions of ICDAS code 3-6
  • known hypersensitivity to one of the ingredients of the toothpastes to be tested
  • systemic disorders interfering with salivary function or flow
  • regular medication intake interfering with salivary function or flow
  • need for antibiotic prophylaxis during dental treatments
  • participation in any other clinical study within the past 3 months or ongoing
  • lack of intellectual or physical ability to conduct the study properly
  • any other reason that, in the opinion of the investigator, disqualifies the subject from participating in the study

About Dr. Kurt Wolff Gmbh & Co. Kg

Dr. Kurt Wolff GmbH & Co. KG is a distinguished pharmaceutical company specializing in dermatological products and innovative therapies. With a strong commitment to research and development, the company focuses on creating effective solutions for skin health, leveraging advanced scientific methodologies and clinical trials to ensure the efficacy and safety of its products. Renowned for its expertise in dermatology, Dr. Kurt Wolff emphasizes quality and patient-centric approaches, aiming to improve the lives of individuals with various skin conditions through evidence-based treatments and ongoing clinical research initiatives.

Locations

Poznan, Poland

Patients applied

0 patients applied

Trial Officials

Elzbieta Paszynska, Assoc. Prof.

Principal Investigator

Poznan University of Medical Sciences

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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