PET/MRI in the Diagnosis of Chronic Pain
Launched by STANFORD UNIVERSITY · Jun 2, 2018
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how certain brain receptors are involved in chronic pain, which is pain that lasts longer than two months. Researchers want to understand the differences in how a special imaging technique, called PET/MRI, shows pain activity in people with chronic pain compared to healthy individuals. The goal is to see how a specific substance, called \[18F\]-FTC-146, is absorbed in the body and if it can help identify the source of pain.
To be eligible for this study, participants must be at least 18 years old. Healthy volunteers should not have any pain or be taking pain medications. Those with chronic pain must have a pain level of at least 4 out of 10. All participants need to have a negative Covid test within 72 hours of their scan, regardless of their vaccination status. If you join this study, you can expect to undergo a PET/MRI scan, which is a safe and non-invasive way to look at your body. This research could lead to better understanding and treatment options for chronic pain in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- Healthy Volunteers:
- • 1. At least 18 years old.
- • 2. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan.
- Pain Patients:
- • 1. At least 18 years old.
- • 2. Chronic pain (nociceptive, neuropathic or mixed pain) lasting greater than 2 months.
- • 3. Pain level of at least 4/10 on a 0-10 Comparative Pain Scale.
- • 4. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan.
- Exclusion Criteria:
- Healthy Volunteers:
- • 1. Pain
- • 2. Pain Medication
- • 3. MRI incompatible
- • 4. Pregnant or nursing
- • 5. Non-English speaker
- • 6. Claustrophobic
- Pain Patients:
- • 1. MRI incompatible
- • 2. Pregnant or nursing
- • 3. Non-English speaker
- • 4. Claustrophobic
About Stanford University
Stanford University is a prestigious academic institution renowned for its cutting-edge research and innovation in healthcare and medicine. As a clinical trial sponsor, Stanford leverages its extensive resources, including a collaborative network of world-class researchers and state-of-the-art facilities, to advance medical knowledge and improve patient care. The university is committed to conducting rigorous, ethical research that adheres to the highest standards of scientific integrity, fostering an environment where groundbreaking discoveries can translate into effective clinical applications. Through its clinical trials, Stanford aims to address critical health challenges and contribute to the development of novel therapies and treatment strategies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Stanford, California, United States
Patients applied
Trial Officials
Anand Veeravagu, MD
Principal Investigator
Stanford University Department of Neurosurgery
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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