Zinc Oxide Versus Petrolatum Following Skin Surgery
Launched by MELISSA PUGLIANO-MAURO · Jun 16, 2018
Trial Information
Current as of May 25, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effectiveness of zinc oxide ointment compared to petrolatum (a common skin ointment) for healing surgical scars. If you're an adult who has had a surgical incision of at least 4.5 cm on non-scalp skin and your site is healing well without infection, you might be eligible to participate. The study is looking for participants who are 18 years and older and have a symmetrical scar that isn’t infected.
As a participant, you would apply either zinc oxide or petrolatum to each half of your scar daily for one month. You would also keep a log of your routine and return for follow-up visits at one week, four weeks, eight weeks, and six months after your surgery. During these visits, doctors will assess your scar using photographs and a special scoring system to evaluate its appearance, healing, and any complications. Additionally, you'll receive parking validation for your visits and a gift bag with hypoallergenic skin care products once the study is complete. This research will help us understand which ointment may be better for scar healing.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. ≥ 18 years of age
- • 2. Linear closure, non-scalp site
- • 3. ≥ 4.5 cm in length (final incision/closure length)
- • 4. End to end symmetry (surgical site is not grossly asymmetric from end to end)
- • 5. Grossly uninfected site
- Exclusion Criteria:
- • 1. ≤ 18 years
- • 2. Visibly asymmetric linear scar
- • 3. Grossly infected surgical site
- • 4. History of allergy to topical zinc oxide
About Melissa Pugliano Mauro
Melissa Pugliano-Mauro is a dedicated clinical trial sponsor with a focus on advancing innovative therapeutic solutions through rigorous research and development. With a strong background in clinical operations and regulatory compliance, she leads initiatives that prioritize patient safety and efficacy in treatment methodologies. Her commitment to fostering collaboration among multidisciplinary teams ensures the successful execution of clinical trials, driving progress in the field of medicine. Through a meticulous approach to study design and implementation, Melissa aims to contribute to the advancement of healthcare and improve outcomes for patients globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pa, Pennsylvania, United States
Patients applied
Trial Officials
Lauren Crow, MD
Principal Investigator
Resident Physician, PGY-3
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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