High Intensity Functional Image Guided Vmat Lung Evasion

Launched by PETER MACCALLUM CANCER CENTRE, AUSTRALIA · Jun 13, 2018

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years;
• • Written informed consent has been provided.
• • Histologically or cytologically confirmed Non-Small Cell Lung Cancer
• • Eastern Cooperative Oncology Group (ECOG) performance status 0-2 within 2 weeks prior to registration
• • Locally advanced disease (stage IIIA, IIIB, IIIC as per American Joint Committee on Cancer AJCC, 8th ed.) as confirmed on staging 18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose (FDG) PET/CT
• • No evidence of metastatic intracranial disease on CT brain with contrast or MRI
• • Willing to participate in the full follow up schedule
• • Planned for treatment with curative intent
• Exclusion Criteria:
• • Participant is not able to tolerate supine position on PET/CT bed for the duration of the PET/CT acquisitions, is not cooperative, or needs continuous nursing (e.g. patient from Intensive Care Unit) or is unable to attend full course of follow up visits
• • Pregnancy or Breast-feeding
• • If history of a prior extra thoracic invasive malignancy (except non-melanomatous skin cancer) must be free from recurrence for a minimum of 3 years at the time of registration
• • Prior radiotherapy to the lungs or mediastinum (a history of prior breast radiotherapy is not an exclusion)
• • Prior known history of interstitial lung disease \* A history of renal impairment or reaction to iodine contrast is not an exclusion criteria, if a patient has medical comorbidities that exclude the use of iodine contrasts, these exploratory investigations can be omitted.