Modeling and Closed-loop Control of Depth of Anaesthesia

Launched by UNIVERSITY OF LJUBLJANA · Jun 14, 2018

Keywords

ClinConnect Summary

This clinical trial is looking at how different anesthetic medications affect the depth of anesthesia during specific surgeries, including eye surgeries and brain surgeries, as well as for patients who need sedation in the intensive care unit (ICU). The goal is to create a new system that can better control how anesthesia is given, making the process safer for patients. Researchers will study how the medications work in the body and develop algorithms, which are like smart instructions, to improve the administration of anesthesia.

To participate in this study, patients should be having vitreoretinal or brain surgery under general anesthesia, or need sedation in the ICU, and must be classified as ASA 1-3 (a way to assess the patient's health before surgery). Those with higher health risks, certain medical conditions, or who are taking specific medications may not be eligible. If you join the trial, you can expect to be part of a process that aims to enhance the safety and effectiveness of anesthesia, contributing to better outcomes for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients having vitroretinal surgery in general anaesthesia
• • patients having brain surgery in general anaesthesia
• • patients needing sedation in ICU
• • ASA 1-3
• Exclusion Criteria:
• • ASA \> 3
• • BMI \> 35
• • drug addicts
• • patients taking psychotropic medicines
• • patients taking opioid analgesics (including tramadol)
• • severe psychiatric disease
• • central nervous system disease (except the reason for surgery)
• • arrhythmia affecting or preventing the measurements (e.g. chronic atrial fibrillation)
• • patients that received benzodiazepines