MitoQ Supplementation and Cardiovascular Function in Healthy Men and Women

Launched by UNIVERSITY OF COLORADO, DENVER · Jul 2, 2018

Keywords

ClinConnect Summary

This clinical trial is looking at whether a supplement called MitoQ, which is designed to help improve the function of our cells' energy factories (mitochondria), can enhance heart health in people who are generally healthy but may have some mild heart function issues, specifically diastolic dysfunction. The study is currently active, meaning they are still gathering data, but they are not currently recruiting new participants.

To be eligible for this study, participants need to be between 50 and 75 years old and should not exercise vigorously more than three times a week. They should also be nonsmokers and in good health according to their medical history and tests. However, individuals with a history of cancer or heart disease, those who are taking certain medications, or women who have had their period in the past year cannot participate. If you join this study, you will be asked to take the MitoQ supplement and undergo tests to see how it affects your heart and blood vessel function. This trial aims to learn more about how MitoQ could potentially help improve cardiovascular health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. 50 - 75 years of age
• • 2. sedentary-to-recreationally active (\<3 days of vigorous exercise);
• • 3. nonsmokers;
• • 4. healthy, as determined by medical history, physical examination, standard blood chemistries.
• Exclusion Criteria:
• • 1. history of cancer
• • 2. history of cardiovascular disease
• • 3. unwilling or unable to take MitoQ supplement;
• • 4. taking antioxidant vitamins, corticosteroids, or anti-inflammatory medications (e.g., aspirin);
• • 5. taking sex hormone therapy
• • 6. presence of menses within last 1 year;
• • 7. taking any other medications (e.g., antihypertensives, lipid lowering medications) that would interact with MitoQ or impact CV function