Investigation of Hemoglobin Oxygenation With Third Harmonic Generation Microscopy

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Aug 1, 2018

Keywords

ClinConnect Summary

Recently, oximeter, detecting the spectral response at wavelengths of 660nm and 940nm, is widely used to measured oxygenation status. Its low spatial resolution and limited penetration depth in human skin, however, restrict the oximeter in clinical application especially for early detection of cancer. In early-stage cancer development, angiogenesis and oxygen depletion around tumor are two important indicators of tumor growth. If an angiogenesis and low oxygenation status can be identified simultaneously, the investigators can point out the early-stage tumor from normal tissue easily.

The ...

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Eligibility criteria

• Inclusion Criteria:
• • older than 20 years old
• Exclusion Criteria:
• • Vulnerable groups, such as pregnant women, prisoners, students, mentally handicapped, aborigines, etc.