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Search / Trial NCT03620266

Effects of Bilberry and Oat Intake After Type 2 Diabetes and/or MI

Launched by OLE FROBERT, MD, PHD · Aug 2, 2018

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

Acute Myocardial Infarction Diet Therapy Anthocyanin Bilberry Bush Exercise Capacity Cholesterol Beta Glucans Type 2 Diabetes Mellitus

ClinConnect Summary

This clinical trial is studying the effects of bilberry and oat intake on heart health for patients who have type 2 diabetes or have recently experienced a heart attack (myocardial infarction). Researchers want to find out if adding dried bilberry and special oat bran to the diet can lower bad cholesterol (LDL) and improve exercise capacity compared to a standard supplement. Participants will be randomly assigned to one of four groups for three months, and the study will also look at other health markers like inflammation and blood sugar levels.

To be eligible for the trial, participants should be at least 18 years old and have a confirmed diagnosis of type 2 diabetes or have had a heart attack within the last three years. They should also be on a specific cholesterol-lowering medication called atorvastatin. Participants will receive guidance on what to expect during the trial, including regular check-ins and assessments of their health. This study aims to explore a safe and cost-effective dietary approach to help reduce health risks for individuals with diabetes and heart issues.

Gender

ALL

Eligibility criteria

  • Inclusion criteria
  • Confirmed T2DM diagnosis (any treatment modality accepted) and/or within 3 years post STEMI or NSTEMI
  • Completed coronary angiography/PCI
  • Male and female subjects ≥18 years
  • Allocated to atorvastatin at a daily dose of 80 mg (only eligible for patients enrolled up to 7 days post MI and not for T2D subjects)
  • Written informed consent
  • Exclusion criteria
  • Emergency coronary artery bypass grafting
  • \<18 years of age
  • LDL cholesterol \<2.0 mmol/L
  • Daily intake or the intent to initiate daily intake of bilberry in any form or daily intake of \>15 g of oatmeal or equivalent
  • Food allergy/intolerance to gluten, bilberries or legumes
  • Previous randomization in the BioDiaMI trial
  • Inability to provide informed consent

About Ole Frobert, Md, Phd

Dr. Ole Frobert, MD, PhD, is a distinguished clinical trial sponsor with extensive expertise in cardiovascular medicine and clinical research. With a robust academic background and a commitment to advancing healthcare, Dr. Frobert leads innovative studies aimed at improving patient outcomes through evidence-based therapies. His collaborative approach fosters strong partnerships within the research community, ensuring rigorous methodologies and adherence to ethical standards. Dr. Frobert's dedication to scientific excellence and patient-centered care positions him as a pivotal figure in the development of novel treatment strategies.

Locations

Odense, , Denmark

Falun, , Sweden

Gothenburg, , Sweden

Karlstad, , Sweden

Lund, , Sweden

Västerås, , Sweden

örebro, , Sweden

Aarhus, , Denmark

Patients applied

0 patients applied

Trial Officials

Ole Frobert, Prof

Study Director

Department of Cardiology, Örebro Univerity Hospital, 701 85 Örebro, Sweden

Cecilia Bergh, PhD

Principal Investigator

Clinical Epidemiology and Biostatistics, School of medical Sciences, örebro University, Sweden

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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