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Search / Trial NCT03621969

Technology Development for Physical Rehabilitation of Patients With Upper Extremity Motor Deficits (RePlay)

Launched by THE UNIVERSITY OF TEXAS AT DALLAS · Aug 8, 2018

Trial Information

Current as of August 02, 2025

Completed

Keywords

Vagus Nerve Stimulation

ClinConnect Summary

The groundbreaking therapy developed at Texas Biomedical Device Center (TXBDC) , called Targeted Plasticity Therapy (TPT) pairs traditional motor, sensory, and cognitive rehabilitation with precise stimulation of the vagus nerve, to guide such robust and specific plasticity to treat a wide range of neurological deficits. The success of this concomitant therapy will be furthered, in part, through the development and use of mechanical devices aimed at measuring the effects of rehabilitation in patients with an upper extremity neurological deficit, e.g. from SCI. These devices are small hand c...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Partial upper limb impairment in one or both arms as a result of a neurological injury or disease
  • Age 18-65
  • Exclusion Criteria:
  • Emotional disability that would interfere with participation as determined by Dr.
  • Wigginton
  • Inability to understand instructions in English
  • No upper limb movement
  • Incarcerated individuals
  • For Phase II, anticipated inability to complete study visits

About The University Of Texas At Dallas

The University of Texas at Dallas (UT Dallas) is a leading research institution dedicated to advancing knowledge and innovation across various disciplines, including health sciences and clinical research. As a clinical trial sponsor, UT Dallas leverages its robust academic infrastructure and interdisciplinary expertise to conduct rigorous studies aimed at improving patient outcomes and enhancing medical practices. The university fosters collaboration among researchers, clinicians, and industry partners, ensuring that its clinical trials adhere to the highest ethical standards and scientific integrity. Through its commitment to research excellence, UT Dallas aims to contribute significantly to the advancement of healthcare solutions and the understanding of complex medical conditions.

Locations

Addison, Texas, United States

Richardson, Texas, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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