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Search / Trial NCT03623360

Functional MRI to Determine Severity of Cirrhosis

Launched by UNIVERSITY OF LEEDS · Aug 7, 2018

Trial Information

Current as of July 23, 2025

Unknown status

Keywords

Gadoxetate Disodium

ClinConnect Summary

This is a pilot study to investigate the feasibility of a novel MRI technique to assess the severity of liver cirrhosis and predict complications based on functionality and perfusion measurements whilst maintaining image quality.

Recruitment:

Twenty (20) patients with cirrhosis who attend the Leeds Liver Unit at St James's University Hospital will be purposively selected by members of the research team who are also part of the usual care team for these patients in advance of scheduled clinic visits. The selection will be in a way to encompass the full clinical spectrum of liver function w...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients who have been diagnosed with liver cirrhosis using standard methods (liver biochemistry, ultrasound based elastography and liver biopsy).
  • Exclusion Criteria:
  • Pregnancy
  • Allergy/intolerance to Gadolinium based contrast agents
  • Severe renal impairment
  • Severe respiratory disease
  • Inability to undergone MRI due to the presence of metal or electronic implants affected by the magnetic field.

About University Of Leeds

The University of Leeds is a prestigious research institution located in the United Kingdom, renowned for its commitment to advancing knowledge through innovative research and education. As a clinical trial sponsor, the University of Leeds leverages its diverse expertise and collaborative environment to facilitate high-quality clinical studies that aim to improve health outcomes and contribute to the scientific community. The university fosters interdisciplinary partnerships, ensuring rigorous methodologies and ethical standards in its research initiatives. By integrating cutting-edge technologies and a patient-centered approach, the University of Leeds plays a vital role in translating research findings into practical applications for healthcare improvement.

Locations

Leeds, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Ian Rowe, Dr

Principal Investigator

University of Leeds

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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