Functional MRI to Determine Severity of Cirrhosis
Launched by UNIVERSITY OF LEEDS · Aug 7, 2018
Trial Information
Current as of July 24, 2025
Unknown status
Keywords
ClinConnect Summary
This is a pilot study to investigate the feasibility of a novel MRI technique to assess the severity of liver cirrhosis and predict complications based on functionality and perfusion measurements whilst maintaining image quality.
Recruitment:
Twenty (20) patients with cirrhosis who attend the Leeds Liver Unit at St James's University Hospital will be purposively selected by members of the research team who are also part of the usual care team for these patients in advance of scheduled clinic visits. The selection will be in a way to encompass the full clinical spectrum of liver function w...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients who have been diagnosed with liver cirrhosis using standard methods (liver biochemistry, ultrasound based elastography and liver biopsy).
- Exclusion Criteria:
- • Pregnancy
- • Allergy/intolerance to Gadolinium based contrast agents
- • Severe renal impairment
- • Severe respiratory disease
- • Inability to undergone MRI due to the presence of metal or electronic implants affected by the magnetic field.
About University Of Leeds
The University of Leeds is a prestigious research institution located in the United Kingdom, renowned for its commitment to advancing knowledge through innovative research and education. As a clinical trial sponsor, the University of Leeds leverages its diverse expertise and collaborative environment to facilitate high-quality clinical studies that aim to improve health outcomes and contribute to the scientific community. The university fosters interdisciplinary partnerships, ensuring rigorous methodologies and ethical standards in its research initiatives. By integrating cutting-edge technologies and a patient-centered approach, the University of Leeds plays a vital role in translating research findings into practical applications for healthcare improvement.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Leeds, , United Kingdom
Patients applied
Trial Officials
Ian Rowe, Dr
Principal Investigator
University of Leeds
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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