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Search / Trial NCT03623672

North American Prodromal Synucleinopathy Consortium

Launched by WASHINGTON UNIVERSITY SCHOOL OF MEDICINE · Aug 6, 2018

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Sleep Rem Rapid Eye Movement Parkinson Lewy Body Disease Dementia With Lewy Bodies Multiple System Atrophy Parasomnia Synuclein Synucleinopathy

ClinConnect Summary

REM sleep behavior disorder (RBD) is a rare disorder where people act out their dreams. People with RBD often, but not always, develop Parkinson's Disease, dementia with Lewy bodies, multiple system atrophy, or other neurodegenerative diseases of the synucleinopathy type. The North American Prodromal Synucleinopathy (NAPS) Consortium was formed with the purpose of enrolling participants with RBD, in anticipation of a future clinical trial of a neuroprotective treatment against synucleinopathies. The NAPS Consortium will collect standardized clinical assessments, biofluids, and other data in...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Idiopathic REM sleep behavior disorder
  • Exclusion Criteria:
  • REM sleep behavior disorder secondary to another cause (ex: narcolepsy, dementia, Parkinson's Disease, etc)
  • Other neurological disorder

About Washington University School Of Medicine

Washington University School of Medicine is a leading academic medical institution renowned for its commitment to advancing healthcare through innovative research, education, and patient care. With a strong emphasis on translating scientific discoveries into practical applications, the institution conducts a diverse array of clinical trials aimed at improving treatment outcomes and enhancing the understanding of various medical conditions. Its collaborative environment fosters partnerships between researchers, clinicians, and community stakeholders, ensuring that the trials not only contribute to scientific knowledge but also address the pressing health needs of diverse populations.

Locations

Rochester, Minnesota, United States

Minneapolis, Minnesota, United States

Boston, Massachusetts, United States

Atlanta, Georgia, United States

Portland, Oregon, United States

Los Angeles, California, United States

Redwood City, California, United States

Saint Louis, Missouri, United States

Sun City, Arizona, United States

Montréal, Quebec, Canada

Patients applied

0 patients applied

Trial Officials

Yo-El Ju, MD

Principal Investigator

Washington University School of Medicine

Bradley Boeve, MD

Principal Investigator

Mayo Clinic

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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