Intestinal Lavage to Promote Enteral Feeding and Prevent Necrotizing Enterocolitis in Extremely Preterm Infants

Launched by UPPSALA COUNTY COUNCIL, SWEDEN · Aug 14, 2018

Keywords

ClinConnect Summary

This clinical trial is studying a method to help extremely preterm infants (those born between 22 and 26 weeks of pregnancy) start feeding more easily and reduce the risk of a serious condition called necrotizing enterocolitis (NEC). Researchers want to see if regularly washing out the intestines with a saline solution can help these infants reach full feeding more quickly and lower the chances of developing NEC or infections. The trial involves two groups of babies: one group will receive the saline washouts, while the other will be treated with standard care. The study will also check how these children develop over the first few years of life.

To be eligible for the trial, infants must be born at Akademiska Hospital in Uppsala and require consent from their guardians. They cannot participate if they have serious birth defects or instability in their circulation shortly after birth. The trial is currently recruiting participants and aims to provide important findings that could improve care for very preterm infants in the future. Parents can expect close monitoring of their babies throughout the study to ensure their safety.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • born at Akademiska hospital in Uppsala
• • gestational age between 22 weeks + 0 days and 26 weeks +6 days
• • written informed consent obtained from both guardians before enrollment in the study.
• Exclusion Criteria:
• • major dysmorphic features consistent with chromosomal abnormality
• • major congenital anomalies, such as gastrointestinal disorders
• • circulatory instability during the first hours of life