AKI Cardiosurgery Diagnostic Study (AKI-CDS)

Launched by UNIVERSITY OF ROSTOCK · Aug 14, 2018

Keywords

ClinConnect Summary

Acute kidney injury (AKI) is an abrupt loss of kidney function and occurs in up to 5-40% of patients who undergo cardiac surgery; dialysis being required in approximately 2-15% of all patients. AKI is a common problem in critically ill patients and is independently from underlying diseases associated with increased morbidity and mortality (to progressive loss of kidney function, cardiovascular disease, and death). Unfortunately, chronic kidney disease is often overlooked in its earliest, most treatable stages. Implementation of novel biomarkers into the clinical practice that reliably ident...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Female or male, at least 18 years old
• • Ability to consent to the study by patient or legal representative
• • Cardiac surgery with use of extracorporeal circulation (ECC)
• • Bypass (\> 2; ACB) or bypass + heart valve surgery
• • Two or three heart-valve operation
• Exclusion Criteria:
• • Dialysis-dependent patients with chronic, end-stage renal failure
• • Pre-existing renal replacement therapy
• • Infused prognosis (expected death in ≤ 12 hours despite maximal therapy)
• • Inability to consent of participation in the research project, of the patient or of the patients representative
• • Aortic surgery
• • Endocarditis
• • (Only) partial sternotomy (eg. aortic valve surgery)