Genetics Of Autoimmunity In Type I Diabetes

Launched by MEDICAL COLLEGE OF WISCONSIN · Aug 23, 2018

Keywords

ClinConnect Summary

This clinical trial, called "Genetics Of Autoimmunity In Type I Diabetes," is studying how type 1 diabetes develops in people. Researchers believe that both genetic factors (things you inherit from your family) and environmental factors (things around you) influence the immune system, which in turn may lead to type 1 diabetes. The study seeks to gather more detailed information about this process by looking at families where at least one member has type 1 diabetes, as well as healthy individuals without any family history of diabetes or autoimmune diseases.

To participate, families must include at least one person diagnosed with type 1 diabetes before age 39, and family members need to be at least 2 years old. Participants will provide a blood sample, answer a short medical history questionnaire, and have their height and weight measured. Some participants may be asked to return for follow-up visits each year for up to 10 years. This study is currently looking for participants of all ages, so if you think you might qualify, it could be a great opportunity to contribute to important research on type 1 diabetes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria (Families):
• • Families where at least one first-degree family member has type 1 diabetes
• • The diabetic proband in the family was diagnosed before the age of 39
• • Family members must be at least 2 years old to participate
• Exclusion Criteria (Families):
• • Families with no history of type 1 diabetes
• • Families with a history of diabetes that is not type 1 (LADA, MODY, type 2 etc.)
• Inclusion Criteria (Controls):
• • No family history of type 1 diabetes or other autoimmune conditions
• • Age 2 or older
• Exclusion Criteria (Controls):
• • Personal or family history of autoimmune disease