Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries

Launched by NEMOURS CHILDREN'S CLINIC · Sep 2, 2018

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a technique called umbilical cord milking (UCM) on newborns who are not vigorous at birth, meaning they need help to start breathing properly. The goal is to find out if UCM can help reduce the chances of serious brain injury, known as hypoxic-ischemic encephalopathy (HIE), or even death compared to the usual practice of clamping the umbilical cord early. This trial is particularly important for babies born in low-resource settings, where immediate care may be limited.

To be eligible for this study, babies must be non-vigorous and born between 35 and 42 weeks of pregnancy. However, babies with certain conditions, like major birth defects or those who are part of multiple births, cannot participate. Families whose babies join the trial can expect to have their child's cord milking assessed right after birth, and the outcomes will be closely monitored to see how it affects their health in the short and long term. This research aims to improve care for newborns in challenging situations and could lead to better treatment practices in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Non-vigorous neonates born between 35-42 weeks
• Exclusion Criteria:
• • Congenital malformation of CNS.
• • Chromosomal abnormalities.
• • Major congenital malformations.
• • Abruption/cutting through the placenta at delivery.
• • Umbilical cord knots or inadequate cord length.
• • Mono-chorionic twins or twins with no information on amnion/chorion.
• • Multiple gestation \>2 .