Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery

Launched by OTTAWA HOSPITAL RESEARCH INSTITUTE · Sep 6, 2018

Keywords

ClinConnect Summary

This clinical trial, called REaCT NSQIP, is studying the effectiveness of two different ways to prepare patients for elective colon surgery. Specifically, it compares using oral antibiotics with not using any antibiotics at all. The goal is to see which method helps patients have a better surgery experience and recovery. This trial is open to all adults aged 18 and older who are scheduled for certain types of planned colon surgeries and do not require a specific type of bowel preparation.

To participate, potential volunteers must be able to give their consent and should not have any allergies or bad reactions to the antibiotics being tested. This study is not for patients undergoing emergency surgeries or those who need a different preparation method for their surgery. If you join the trial, you will help researchers learn more about the best practices for preparing the bowel before surgery, which could lead to improved care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing elective, non-emergency colon, resection surgery or abdominal perineal resection and no other requirements exists for a mechanical bowel preparation (as determined by the operating surgeon)
• • 18 years of age or older
• • Able to provide oral consent
• Exclusion Criteria:
• • Contraindication to the oral antibiotics, including allergies or adverse reactions to either metronidazole or neomycin
• • Undergoing a rectal resection with a planned anastomosis (these patients will all receive MBP)
• • Emergency surgery where no opportunity to administer preoperative oral antibiotics exists
• • Requirement for a MBP (i.e. rectal resection with pelvic anastomosis, intraoperative colonoscopy, or at the discretion of the treating surgeon