Laparoscopic Ovarian Drilling Versus Letrozole In Clomiphene Citrate Resistant Polycystic Ovary

Launched by AIN SHAMS UNIVERSITY · Sep 7, 2018

Keywords

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Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. patients diagnosed as PCOS according to Roterdam (2003) criteria
• • 2. patients with Clomiphene resistance, i.e. failure to ovulate following 100 mg CC for 5 days for at least three cycles.
• • 3. patent fallopian tubes, confirmed by hysterosalpingography or hysteroscopic diagnosis.
• • 4. normal semen analysis parameters of the patients' spouses according to the modified criteria of the World Health Organization.
• • 5. normal serum prolactin, thyroid stimulating hormone and 17-OH progesterone.
• • 6. no systemic disease; no gonadotropin or other hormonal drug treatment during the preceding 3 months.
• Exclusion Criteria:
• • 1- Infertility induced by reasons other than PCOS. 2- uterine cavity lesions or ovarian cyst. 3- \>40 years old. 4- body mass index (BMI) \>26 kg/m2. 5- contraindications to general anesthesia. 6- history of pelvic surgery. 7- other endocrine diseases. 8- a history of liver or kidney disease.
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