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Search / Trial NCT03667105

Evaluation of Two Types of Matrix (Mucograft® and Mucoderm®) Associated With Coronally Advanced Flap

Launched by UNIVERSIDADE ESTADUAL PAULISTA JÚLIO DE MESQUITA FILHO · Sep 10, 2018

Trial Information

Current as of July 03, 2025

Completed

Keywords

ClinConnect Summary

This is a prospective, parallel and controlled clinical trial. The population that will be evaluated in the study will be selected at Institute of Science and Technology (ICT), São José dos Campos, College of Dentistry.

Seventy-five patients presenting gingival recession will be divided in 3 groups:

* Group CAF + XDM (25): Periodontal surgery for root coverage through coronally advanced flap technique plus xenogenous dermal matrix graft Mucoderm®.
* Group CAF + MC (25): Periodontal surgery for root coverage through coronally advanced flap technique plus xenogenous collagen matrix graft Mu...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients presenting Miller class I or II gingival recession in the maxillary canines or premolars;
  • Teeth included in the study should present pulp vitality and no associated with carious or cervical lesion;
  • Patients presenting no signs of active periodontal disease and full-mouth plaque and bleeding score ≤ 20%;
  • Probing depth ˂ 3 mm in the included and adjacent teeth, presenting no signs of bleeding or attachment loss;
  • Patients older than 18 years old;
  • Patients who agreed to participate and signed an informed consent form.
  • Exclusion Criteria:
  • Patients with systemic problems (cardiovascular, blood dyscrasias, immunodeficiency, and diabetes, among others) that will contraindicate the surgical procedure;
  • Patients taking medications known to interfere with the wound healing process or that contraindicate the surgical procedure;
  • pregnant or lactating women;
  • Smokers;
  • Patients who underwent periodontal surgery in the area of interest;
  • Patients with orthodontic therapy in progress.

About Universidade Estadual Paulista Júlio De Mesquita Filho

Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) is a prominent public research university in Brazil, recognized for its commitment to advancing scientific knowledge and innovation in various fields, including health sciences. As a clinical trial sponsor, UNESP leverages its extensive academic resources and interdisciplinary expertise to conduct rigorous clinical research aimed at improving patient outcomes and advancing medical practices. The university fosters collaboration among researchers, healthcare professionals, and industry partners, ensuring adherence to ethical standards and regulatory compliance throughout the research process. UNESP's dedication to excellence in clinical trials contributes significantly to the global body of medical knowledge and public health advancements.

Locations

São José Dos Campos, São Paulo, Brazil

São José Dos Campos, , Brazil

Patients applied

0 patients applied

Trial Officials

Mauro P Santamaria, PhD

Principal Investigator

ICT-UNESP

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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