Spinal Morphine for Postoperative Analgesia in Urology
Launched by CHARLES UNIVERSITY, CZECH REPUBLIC · Sep 17, 2018
Trial Information
Current as of September 01, 2025
Completed
Keywords
ClinConnect Summary
Patients elicited for open prostatectomy or open nephrectomy were randomly divided in 2 groups. Group M were administered preservative-free morphine 250 mcg in 2.5 ml NS intrathecal using 25 G needle in L1/2 - L5/S1 interspaces. Control group (C) were given no intervention. Placebo intrathecal injection in C was not used because of ethical reason. Standard general anaesthesia was used in both groups. After surgery all patients were transferred to urology ICU and were given standard analgesic regimen according to level of pain measured by numeric rating scale (NRS) 0 - 10: NRS \> 3 metamizol...
Gender
ALL
Eligibility criteria
- • Inclusion Criteria
- • elicited open prostatectomy or open nephrectomy
- • Exclusion Criteria
- • drug or alcohol dependence
- • psychiatric drug use
- • ASA classification IV or V
- • general contraindication to neuroaxial injection
About Charles University, Czech Republic
Charles University, located in the Czech Republic, is a prestigious institution renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, the university leverages its extensive academic expertise and state-of-the-art facilities to conduct innovative research that aims to improve patient outcomes and contribute to the global medical community. With a focus on ethical standards and rigorous scientific methodologies, Charles University collaborates with various stakeholders to explore new therapies and enhance healthcare practices, fostering a culture of excellence in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Praha, , Czechia
Patients applied
Trial Officials
Jiri Malek, M.D.
Principal Investigator
3rd Medical Faculty, Charles University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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