The Role of Contrast Enhanced Ultrasound in Appendicitis

Launched by CHILDREN'S MERCY HOSPITAL KANSAS CITY · Sep 25, 2018

Keywords

ClinConnect Summary

This will be a single-center, non-randomized trial that will add to our institution's current diagnostic algorithm using Contrast Enhanced Ultra Sound (CEUS) in subjects who are clinically suspicious for acute appendicitis.

For those who consent to study participation, we propose obtaining a CEUS after the initial gray-scale ultrasound. Once the initial ultrasound is complete, the contrast Lumason® (sulfur hexafluoride lipid type-A microspheres) will be administered through an already existing IV catheter and an abdominal scan will be completed. The patient will then continue with standard...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Present to Children's Mercy Adele Hall campus with a clinical concern for acute appendicitis
• • Age 8 through 17 years
• • seen between Institutional Review Board (IRB) approval date and 12/31/2019
• • Seen Monday- Friday between the hours of 9:00 a.m. and 4:00 pm
• • Has had an IV catheter placed as part of their standard of care
• Exclusion Criteria:
• • Known cardiac abnormality
• • Pulmonary hypertension
• • Known sensitivity to sulfur hexafluoride, polyethylene glycol 4000, distearoylphosphatidylcholine (DSPC), dipalmitoylphosphatidylglycerol sodium (DPPG-Na), or palmitic acid
• • Does not had an IV catheter placed
• • Unable to roll over
• • Unable to assent
• • Pregnant
• • Lactating
• • Received an ultrasound image from a referring facility