Esophageal Balloon Calibration in Assisted Ventilation Mode
Launched by AZIENDA OSPEDALIERO UNIVERSITARIA MAGGIORE DELLA CARITA · Oct 24, 2018
Trial Information
Current as of July 21, 2025
Completed
Keywords
ClinConnect Summary
Assisted ventilatory modes, nowadays, have been proved to reduce complications related to controlled mechanical ventilation. With these modes, ventilatory cycling is under the patient's control to an extent depending on the type of ventilatory modality.
Sigh improves oxygenation and lung mechanics during pressure control ventilation and pressure support ventilation (PSV) in patients with acute respiratory distress syndrome.
In order to better quantify the effects of both PSV and PSV plus Sigh on respiratory mechanics, the esophageal pressure monitoring could be helpful. However, esophagea...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients older than 18 years;
- • undergoing mechanical ventilation for more than 24 hours (in volume-controlled mode) and with readiness to run assisted ventilation;
- Exclusion Criteria:
- • severe COPD with air trapping clinical suspicion;
- • hemodynamic instability requiring inotropic or vasopressor support;
- • any contraindications to esophageal catheter positioning
About Azienda Ospedaliero Universitaria Maggiore Della Carita
Azienda Ospedaliero Universitaria Maggiore della Carità is a leading academic hospital in Italy, renowned for its commitment to advancing healthcare through innovative clinical research and comprehensive patient care. With a focus on a wide range of medical specialties, the institution collaborates with various research entities to conduct rigorous clinical trials aimed at improving treatment outcomes and enhancing medical knowledge. Its state-of-the-art facilities and multidisciplinary approach ensure high-quality standards in research, fostering an environment conducive to scientific discovery and the development of new therapeutic strategies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Novara, , Italy
Patients applied
Trial Officials
Gianmaria Cammarota, MD,PhD
Principal Investigator
"Maggiore della Carità" Hospital, Novara
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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