Remote Ischaemic Postconditioning in the Clinical Setting of NSTEACS and Urgent PCI
Launched by UNIVERSITY COLLEGE, LONDON · Oct 29, 2018
Trial Information
Current as of May 17, 2025
Completed
Keywords
ClinConnect Summary
Patients presenting with Non ST elevation acute coronary syndromes (NSTEACS) - NSTEMI and Unstable angina patients are enrolled in this study.
Eligible patients are approached, with patient information sheets and are consented for involvement into the study. Patients are randomised to intervention or control. Patients randomised to intervention will receive 3 x 5 minutes of forearm ischaemia (with the cuff inflated to 200 mmHg) separated by 5 minutes of reperfusion between each cuff inflation, prior coronary angiography.
This protocol of episodic forearm ischaemia/reperfusion has been dem...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients admitted with NSTEMI/ Unstable angina undergoing percutaneous intervention
- Exclusion Criteria:
- • Known renal failure
- • Known liver disease
- • Peripheral vascular disease involving upper limbs
- • Inability to consent
About University College, London
University College London (UCL) is a leading global research institution renowned for its commitment to advancing healthcare through innovative clinical trials. As a prominent sponsor of clinical research, UCL leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous investigations aimed at improving patient outcomes and addressing pressing medical challenges. The institution fosters collaboration among researchers, healthcare professionals, and industry partners, ensuring that its trials adhere to the highest ethical standards and regulatory guidelines. UCL's dedication to translating scientific discoveries into practical applications underscores its role as a vital contributor to the advancement of medical science and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Derek M Yellon, PhD, FACC
Study Director
University College, London
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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