Programmed Intermittent Epidural Bolus Versus Continuous Infusion in Labour Analgesia

Launched by UNIVERSITÉ DE SHERBROOKE · Nov 2, 2018

Keywords

ClinConnect Summary

This clinical trial is studying two different ways to manage pain during labor: one method uses a programmed intermittent epidural bolus, while the other uses a continuous infusion of medication. The researchers want to find out if the first method, which allows for controlled doses of pain relief, will result in less medication being used compared to the continuous method. This study aims to help improve how women experience pain relief during labor.

To be eligible for this trial, participants must be women aged 18 or older who are in labor and have given consent for an epidural. They should be having their first baby or any subsequent babies and must be in early labor with a cervical dilation of 6 centimeters or less. The trial is currently recruiting participants, and those who join can expect to receive either type of pain relief during their labor while helping researchers learn more about effective pain management options. It's important to know that certain medical conditions or situations, like a breech baby or certain allergies, may prevent someone from participating in the trial.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pregnant nulliparous or multiparous woman in labour
• • Age ≥18 years
• • Obtained consent for epidural analgesia
• • ASA classification I-II-III
• • Early labour (cervical dilation ≤6cm)
• Exclusion Criteria:
• • Pregnancy-related comorbidities (preeclampsia, eclampsia, gestational diabetes, large for gestational age fetus)
• • Prematurity (\<36 weeks of gestation)
• • Multiple gestation
• • Fentanyl allergy or hypersensitivity
• • Patient unable to understand the PCEA
• • Fetal breech position
• • Maternal cardiac pathology and contraindication to Valsalva manoeuvre
• • Patient with a pain visual analog scale (VAS) not ≤1/10 20 minutes after the anesthesiologist's initial bolus
• • Intrathecal catheter or intravascular catheter
• • Accidental dural puncture
• • Patient refusal
• • Patient with a history of chronic pain (pain lasting more than 3 months) or fibromyalgia