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Search / Trial NCT03748069

Influenza Associated Aspergillosis In-depth Investigation

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Nov 16, 2018

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Influenza Ipa Icu Immunology

ClinConnect Summary

This clinical trial, called the "Influenza Associated Aspergillosis In-depth Investigation," is studying how the immune system and lung health are affected in patients with severe pneumonia caused by influenza compared to those with pneumonia not caused by influenza. The researchers want to understand the differences in how these two groups of patients respond when they are in the Intensive Care Unit (ICU).

To participate in this trial, you need to be over 18 years old and admitted to the ICU with breathing difficulties. If you have been diagnosed with influenza, you would be part of the influenza group. If your doctor confirms that you do not have influenza, you would be part of the control group. Participants will undergo various tests and evaluations to help researchers gather important information about these conditions. It's important to note that pregnant women and individuals under 18 cannot participate in this study.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients older than 18 years, admitted to ICU with respiratory distress with microbiologically confirmed diagnosis of influenza (for inclusion in the influenza group)
  • All patients older than 18 years, admitted to ICU for respiratory distress due to community- acquired pneumonia , with a microbiologically confirmed absence of influenza (for inclusion in the control group)
  • Exclusion Criteria:
  • Age \< 18 years old
  • Pregnant women
  • No informed consent

About Universitaire Ziekenhuizen Ku Leuven

Universitaire Ziekenhuizen KU Leuven is a leading academic medical center in Belgium, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. Affiliated with KU Leuven, one of Europe’s premier universities, the institution integrates cutting-edge scientific inquiry with high-quality patient care. It plays a pivotal role in the development and implementation of clinical trials, fostering collaboration between researchers, healthcare professionals, and industry partners to translate scientific discoveries into effective treatments. The hospital's multidisciplinary approach ensures comprehensive patient safety and ethical standards, positioning it as a trusted sponsor in the realm of clinical research.

Locations

Leuven, , Belgium

Leuven, , Belgium

Patients applied

0 patients applied

Trial Officials

Joost Wauters, PhD

Principal Investigator

UZ Leuven

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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