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Search / Trial NCT03753412

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

Launched by BARTS & THE LONDON NHS TRUST · Nov 22, 2018

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Extra Corporeal Membrane Oxygenation (Ecmo) Intensive Care Unit Acquired Weakness (Icuaw) Critical Illness Polyneuromyopathy (Cipm) Ultrasound (Us) Health Related Quality Of Life (Hr Qo L)

ClinConnect Summary

The clinical trial titled "Recovery From ICUAW Following Severe Respiratory and Cardiac Failure" is studying how patients recover from weakness caused by spending time in the intensive care unit (ICU) after experiencing serious heart and lung issues that required a special treatment called ECMO. This trial aims to understand what factors help or hinder recovery from this weakness and how it affects patients' physical abilities and overall quality of life after being critically ill.

To be eligible for this trial, participants must be adults over 18 years old who have experienced severe respiratory or cardiac failure and needed ECMO support. The study is currently looking for volunteers, and anyone who joins can expect to be observed and have their recovery tracked over time. It's important to note that individuals with certain conditions, like a history of strokes or specific neuromuscular diseases, will not be able to participate. This trial seeks to provide valuable insights that could improve recovery for future patients facing similar health challenges.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Above the age of 18
  • Adults with severe cardio-respiratory failure requiring ECMO.
  • Adults who have had personal and professional consultees agree to enrol them in the trial.
  • Exclusion criteria:
  • Previous Stroke
  • Neuromuscular disease
  • Malignancy
  • Underlying neuromuscular disease
  • paediatrics

About Barts & The London Nhs Trust

Barts and The London NHS Trust is a leading healthcare organization in the United Kingdom, renowned for its commitment to delivering high-quality clinical care, research, and education. As a prominent sponsor of clinical trials, the Trust is dedicated to advancing medical knowledge and improving patient outcomes through innovative research initiatives. With a focus on patient safety and ethical standards, Barts and The London NHS Trust collaborates with multidisciplinary teams to explore cutting-edge therapies and interventions across various medical fields, ensuring that trial participants receive the highest level of care and support throughout their involvement.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Mark Griffiths, PhD FRCP

Principal Investigator

Substantive Employee and primary supervisor to PhD student

Julie Sanders, MSc, PhD

Principal Investigator

Director of research and supervisor to PhD student

Ashley Thomas, MSc

Principal Investigator

Substantive employee and PhD student

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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