Exome Sequencing Study in Cardiomyopathy to Identify New Risk Variants

Launched by TONGJI HOSPITAL · Nov 24, 2018

Keywords

ClinConnect Summary

This clinical trial is studying the genetic causes of cardiomyopathy, a condition that affects the heart muscle and can lead to heart failure. Researchers are looking for new genetic changes, called variants, that might help explain why some people develop this condition. The study began in March 2003 and will continue to recruit patients until November 2017. It involves taking blood samples from patients diagnosed with cardiomyopathy, as well as samples from healthy individuals for comparison.

To be eligible for this study, participants must have a diagnosis of cardiomyopathy as defined by the American Heart Association. However, individuals with certain conditions, such as uncontrolled high blood pressure, significant heart valve issues, or those who have recently had cancer treatments, cannot participate. If you join the study, you can expect to have your blood tested to help researchers identify genetic factors related to cardiomyopathy. This research may provide valuable insights that could improve understanding and treatment of this heart condition in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • · Patients diagnosed as cardiomyopathy according to the definition of American Heart Association
• Exclusion Criteria:
• • Uncontrolled hypertension significant valvular disease
• • Mild ischemic heart disease
• • Significant systemic infection
• • Thyroid-induced cardiomyopathy
• • Excessive alcohol consumption
• • Precious cancer treatment including irradiation
• • Refusal to participate in the study