Clomiphene Citrate, Estradiol and Sildenafil for Induction of Ovulation in Unexplained Infertility
Launched by NESREEN ABDEL FATTAH ABDULLAH SHEHATA · Nov 25, 2018
Trial Information
Current as of July 21, 2025
Completed
Keywords
ClinConnect Summary
Clomiphene citrate has been widely used alone, and in combination with intrauterine insemination (IUI), for treatment of unexplained subfertility, The mechanism of action is based on its mixed estrogenic and antiestrogenic properties. Clomiphene is frequently used to treat unexplained female infertility by inducing multifollicular response and correcting potential subtle ovulatory dysfunction .,)The American Society for Reproductive Medicine,2003).
The use of clomiphene citrate decreases the uterine blood flow during the early luteal phase, a periimplantation stage., )The American College ...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women whose infertility tests were normal then diagnosed as unexplained infertility.
- Exclusion Criteria:
- • Any cause of infertility male factor, tubal or ovarian.
- • Chronic illness as cardiac or renal disease
- • Any contraindication for used drugs
About Nesreen Abdel Fattah Abdullah Shehata
Nesreen Abdel Fattah Abdullah Shehata is a dedicated clinical trial sponsor with a focus on advancing medical research and improving patient outcomes. With a strong background in clinical sciences and a commitment to ethical standards, she oversees the planning, execution, and management of clinical trials across various therapeutic areas. Her leadership fosters collaboration among multidisciplinary teams, ensuring rigorous adherence to regulatory guidelines and best practices. By prioritizing patient safety and data integrity, Nesreen plays a pivotal role in the development of innovative therapies that aim to address unmet medical needs.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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