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Search / Trial NCT03762733

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Launched by NATIONAL CANCER INSTITUTE (NCI) · Dec 1, 2018

Trial Information

Current as of July 24, 2025

Enrolling by invitation

Keywords

Biobanking Tissue Repository Genetic Analysis Natural History

ClinConnect Summary

Background:

Increased understanding of the genomic variations of cancer through laboratory evaluations can result in breakthroughs in treatment and improved patient outcomes.

Exceptional responders on clinical trials may have mutational characteristics that are unique and unknown, necessitating identification.

Current drug development strategies employ precision oncology. This approach identifies molecular targets, with therapies being either chosen or developed to interact with the specific target.

The collection and banking of a variety of tissue samples for future translational studi...

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • Adult subject (age 18 and older) co-enrolled on a trial, or otherwise undergoing consultation, screening, or follow up on existing protocols conducted at the NIH Clinical Center, who are evaluated in the Women s Malignancies Branch Clinic.
  • * Participant or biological relative of a participant, as follows:
  • Participant with a histologically confirmed breast cancer or other gynecologic malignancy; histopathology of the biopsy tissue must be
  • confirmed by the NCI Laboratory of Pathology, prior to banking of the tissue on this protocol.
  • Biological relative (1st 3rd degree) of a participant who meets the eligibility of histologically confirmed malignancy per above
  • criterion.
  • Subject willingness and ability to provide informed consent.
  • Subject willingness to provide tissue samples for banking.
  • EXCLUSION CRITERIA:
  • - Pregnant individuals are not eligible to take part; pregnancy will be assessed using clinical criteria (medical history and physical exam).

About National Cancer Institute (Nci)

The National Cancer Institute (NCI) is a prominent component of the National Institutes of Health (NIH), dedicated to advancing cancer research and improving patient outcomes through innovative clinical trials. As a leading sponsor of cancer-related studies, NCI focuses on facilitating the development of new therapies, enhancing prevention strategies, and understanding the biology of cancer. The institute collaborates with academic institutions, healthcare providers, and industry partners to conduct rigorous clinical trials that aim to translate scientific discoveries into effective treatments. NCI’s commitment to fostering a robust research environment supports the mission to eliminate cancer as a major health problem.

Locations

Bethesda, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Jung-Min Lee, M.D.

Principal Investigator

National Cancer Institute (NCI)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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