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Search / Trial NCT03767426

The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

Launched by BETH ISRAEL DEACONESS MEDICAL CENTER · Dec 5, 2018

Trial Information

Current as of June 24, 2025

Recruiting

Keywords

Emotion Memory Sleep Sleep Deprivation

ClinConnect Summary

This clinical trial is studying how sleep deprivation—meaning not getting enough sleep—and recovery sleep—getting sleep after being deprived—affect our emotions and how we remember emotional experiences. Researchers want to understand three main things: how lack of sleep and normal sleep change the way we process emotions, what happens in our brains and bodies during this process, and whether getting good sleep afterward can help fix the effects of not sleeping enough. This is important because many people are sacrificing sleep for work or social activities, and understanding sleep's role in managing emotions could help those who are under more stress, like new parents or healthcare workers.

To participate in this trial, you need to be between 18 and 65 years old, willing to follow the study’s guidelines, and able to undergo an MRI scan (a type of brain scan). You should have normal vision (or corrected vision) and must not have any sleep problems or a history of mental health issues. Participants will be asked to avoid alcohol and recreational drugs during the study. If you join, you can expect to contribute to valuable research that could improve our understanding of sleep and emotional health.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • willing and able to follow the protocol
  • willing and able to meet inclusion criteria for fMRI scanning
  • willing to refrain from alcohol and recreational drugs for the duration of the protocol
  • normal or corrected to normal vision is required
  • Exclusion Criteria:
  • self-reported sleep disturbances
  • left-handedness or ambidexterity
  • a history of mental illness or neurological disorder
  • the use of any drugs that could affect either sleep or cognitive functioning (e.g., sleeping pills or antidepressants)

About Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center (BIDMC) is a leading academic medical center located in Boston, Massachusetts, affiliated with Harvard Medical School. Renowned for its commitment to cutting-edge research and innovation in healthcare, BIDMC fosters a collaborative environment that integrates patient care, education, and scientific investigation. The center actively sponsors clinical trials across a variety of disciplines, aiming to advance medical knowledge and improve patient outcomes. With a focus on translational medicine, BIDMC's research initiatives engage multidisciplinary teams to address complex health challenges and translate findings into effective therapeutic strategies.

Locations

Boston, Massachusetts, United States

Boston, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Tony Cunningham, PhD

Principal Investigator

Beth Israel Deaconess Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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