Enhancing Renal Graft Function During Donor Anesthesia
Launched by NAZMY EDWARD SEIF · Dec 17, 2018
Trial Information
Current as of November 11, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how to improve the function of a transplanted kidney during surgery. It focuses on comparing three different methods: using a substance called Mannitol, a medication called Dopamine, and making sure patients are well-hydrated. The goal is to find out which method helps the new kidney work better right after the transplant.
To participate in this trial, you need to have end-stage renal disease and be scheduled for a living-donor kidney transplant. Unfortunately, people with severe heart or liver problems, or those with certain blood disorders, cannot take part. If you join the study, you will receive one of the three treatments during your surgery, and researchers will monitor how well your new kidney performs afterward. This research is important because it could lead to better outcomes for kidney transplant patients in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • end-stage renal disease, for living-donor kidney transplantation
- Exclusion Criteria:
- • severe cardiac or hepatic dysfunction
- • coagulopathy
About Nazmy Edward Seif
Nazmy Edward Seif is a dedicated clinical trial sponsor committed to advancing medical research and innovation. With a focus on developing novel therapeutic solutions, the organization collaborates with leading healthcare professionals and institutions to design and execute rigorous clinical studies. Emphasizing patient safety and ethical standards, Nazmy Edward Seif strives to facilitate the seamless transition of groundbreaking therapies from the laboratory to clinical practice, ultimately aiming to improve patient outcomes and enhance public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, Egypt
Patients applied
Trial Officials
Nazmy E Seif, MD
Study Chair
Kasr Al-Ainy Hospital, Cairo University
Ahmed M Elbadawy, MD
Study Director
Kasr Al-Ainy Hospital, Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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