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Search / Trial NCT03778944

Enhancing Renal Graft Function During Donor Anesthesia

Launched by NAZMY EDWARD SEIF · Dec 17, 2018

Trial Information

Current as of November 11, 2025

Recruiting

Keywords

Mannitol Dopamine Perfusion Renal Graft Donor Anesthesia

ClinConnect Summary

This clinical trial is studying how to improve the function of a transplanted kidney during surgery. It focuses on comparing three different methods: using a substance called Mannitol, a medication called Dopamine, and making sure patients are well-hydrated. The goal is to find out which method helps the new kidney work better right after the transplant.

To participate in this trial, you need to have end-stage renal disease and be scheduled for a living-donor kidney transplant. Unfortunately, people with severe heart or liver problems, or those with certain blood disorders, cannot take part. If you join the study, you will receive one of the three treatments during your surgery, and researchers will monitor how well your new kidney performs afterward. This research is important because it could lead to better outcomes for kidney transplant patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • end-stage renal disease, for living-donor kidney transplantation
  • Exclusion Criteria:
  • severe cardiac or hepatic dysfunction
  • coagulopathy

About Nazmy Edward Seif

Nazmy Edward Seif is a dedicated clinical trial sponsor committed to advancing medical research and innovation. With a focus on developing novel therapeutic solutions, the organization collaborates with leading healthcare professionals and institutions to design and execute rigorous clinical studies. Emphasizing patient safety and ethical standards, Nazmy Edward Seif strives to facilitate the seamless transition of groundbreaking therapies from the laboratory to clinical practice, ultimately aiming to improve patient outcomes and enhance public health.

Locations

Cairo, Egypt

Patients applied

0 patients applied

Trial Officials

Nazmy E Seif, MD

Study Chair

Kasr Al-Ainy Hospital, Cairo University

Ahmed M Elbadawy, MD

Study Director

Kasr Al-Ainy Hospital, Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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