Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients with Sciatica
Launched by TAIPEI MEDICAL UNIVERSITY HOSPITAL · Jan 10, 2019
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying different treatments for sciatica, a condition that causes pain along the sciatic nerve, often due to issues like herniated discs or spinal stenosis. The trial will compare three types of treatments: steroid injections, acupuncture, and platelet-rich plasma injections. The aim is to find out which treatment is the most effective and safe for relieving sciatica symptoms.
To participate, individuals must be between 20 and 80 years old and have specific types of sciatica that can be confirmed through medical imaging, like X-rays or MRIs. Participants should be able to follow the trial's guidelines and complete the necessary treatments and assessments. It's important to note that some people will not be eligible, such as those with severe neurological issues or recent surgeries related to their back. If you join the trial, you can expect to receive one of the treatments being studied and help contribute to important research that could improve care for others with sciatica.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Female or male, 20 to 80 years of age.
- • 2. Participants who had dermatome between L3 to S1, or participants whose straight leg raising test was positive, or participants had Meyerding Grade I to II spondylolisthesis or herniated intervertebral disc or spinal stenosis diagnosed by X-rays, Magnetic resonance imaging or computed tomography.
- • 3. Participants whose sciatica symptom doesn't have occur time limit.
- • 4. Participants who agreed to follow the trial protocol.
- • 5. Participants who could complete the study treatment and assessments.
- • 6. Participants who had steroid or pain control injection can participate the study after receiving injection more than 3 days.
- Exclusion Criteria:
- • 1. Participants with severe progressive neurological symptoms (e.g. cauda equina compression).
- • 2. Participants who had undergone surgery for lumbar disc herniation within 6 months.
- • 3. Participants whose sciatica symptom wasn't caused by lumbar radiculopathy.
- • 4. Participants with cardiovascular, liver, kidney, or hematopoietic system diseases, severe psychiatric or psychological disorder, or cancer.
- • 5. Women who were pregnant.
- • 6. Participants with a pacemaker, metal allergy, or severe fear of needles.
About Taipei Medical University Hospital
Taipei Medical University Hospital is a leading medical institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital integrates cutting-edge medical practices with comprehensive patient care, fostering an environment that promotes scientific discovery and the development of new therapies. With a strong commitment to ethical standards and regulatory compliance, Taipei Medical University Hospital collaborates with multidisciplinary teams to enhance patient outcomes and contribute to the global medical community. Through its extensive research programs, the hospital aims to address critical health challenges and improve the quality of life for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Taipei City, , Taiwan
Patients applied
Trial Officials
Ray-Jade Chen, PhD
Study Chair
Taipei Medical University Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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