Walking Gait Biomechanics Following Knee Joint Effusion
Launched by DUKE UNIVERSITY · Jan 14, 2019
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how a wearable sensor can detect changes in knee joint loading, which refers to the pressure and stress on the knee joint, especially when there is fluid buildup (called joint effusion) in the knee. The goal is to see if this affordable device can effectively monitor changes in how the knee works during walking, which is important for people with knee injuries or osteoarthritis. The study will include 25 healthy adults aged 18 to 35 who are physically active, and it aims to gather data on their movement and muscle function during walking.
Participants will have three sessions at the lab, where they will first learn about the study, then undergo testing, and finally have their knee health assessed. To be eligible, participants must be physically active and have no recent serious injuries or medical conditions that could affect their knee. While there are some risks associated with the study, such as the knee joint effusion procedure, these will be managed carefully. Overall, this research could help improve how we monitor knee health in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Male and female
- • Chronological age 18-35 at the time of study participation
- • Physically active (at least 30 minutes of physical activity, 3x/week)
- • Tegner Activity Scale score at least 5/10
- Exclusion Criteria:
- • History of lower extremity or lumbar spine surgery.
- • History of lower extremity or lumbar spine injury in the prior 6 months.
- • History of major ligamentous damage.
- • Current knee pain.
- • Known neurological condition, autoimmune condition, cardiovascular disease.
- • History of epilepsy, seizures, concussion within the prior 6 months.
- • Currently taking pain altering medication.
- • Fear of needles
- • Unable to read and understand English language
- • Pregnancy
About Duke University
Duke University, a leading academic and research institution located in Durham, North Carolina, is renowned for its commitment to advancing healthcare through innovative clinical research. With a strong emphasis on interdisciplinary collaboration, Duke conducts a wide array of clinical trials aimed at developing cutting-edge therapies and improving patient outcomes across various medical fields. The university's Clinical Research Institute provides comprehensive support for trial design, implementation, and regulatory compliance, ensuring that all research adheres to the highest ethical and scientific standards. Duke’s dedication to translating research findings into effective clinical practices underscores its role as a pivotal contributor to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Durham, North Carolina, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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