Laser vs Hyaluronic Acid for GSM in Breast Cancer

Launched by MEDICAL UNIVERSITY OF GRAZ · Jan 24, 2019

Keywords

ClinConnect Summary

This clinical trial is exploring two different treatments for women who have experienced breast cancer and are suffering from genitourinary symptoms of menopause (GSM), such as dryness, burning, irritation, and discomfort during sexual activity. The study compares the effects of a laser treatment and a hyaluronic acid suppository, both of which aim to relieve these uncomfortable symptoms. Women aged 18 to 80 who have a history of breast cancer and have completed their initial cancer treatment may be eligible to participate.

Participants in the trial will be randomly assigned to receive either the laser treatment, which involves two sessions over a month, or the hyaluronic acid suppository, which they will use daily for the first ten days and then every third day for three months. Throughout the trial, participants will fill out questionnaires to help evaluate their symptoms and quality of life before and after the treatment. It's important to note that women currently dealing with certain conditions, such as infections or abnormal bleeding, will not be eligible for this study.

Gender

FEMALE

Eligibility criteria

• • Inclusion criteria
• • genital symptoms of dryness/ burning/ irritation
• • and/ or lack of lubrication during sexual intercourse/ sexual discomfort or pain
• • and/or symptoms of urgency and dysuria or recurrent urinary tract infection
• • Age 18-80
• • History of BC and/ or DCIS
• • Completed locoregional therapy
• • Current antihormonal therapy for BC possible
• • Intravaginal treatment with creams/ suppositories other than study medicationshould be ceased during the trial
• Exclusion criteria:
• • Current or past genitourinary malignancy
• • Abnormal PAP smear
• • Current genitourinary tract infection
• • Abnormal uterine bleeding
• • photosensitive medication