Correlation Between Trans Esophageal Pressure and Non-invasive Respiratory Support Failure in Patients With Acute Hypoxic Respiratory Failure
Launched by UNIVERSITY OF MODENA AND REGGIO EMILIA · Jan 30, 2019
Trial Information
Current as of August 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how certain measurements taken from inside the body, specifically the pressure in the esophagus, relate to the effectiveness of non-invasive breathing support for patients experiencing acute hypoxic respiratory failure. This condition means that patients have trouble getting enough oxygen into their blood, which could be due to various reasons, including infections like COVID-19. The aim is to see if understanding these pressures can help predict when non-invasive support might not be working as well as it should.
To participate in this study, individuals must be over 18 years old and have acute hypoxic respiratory failure, meaning their oxygen levels are critically low. However, people with certain conditions like severe lung swelling, chest deformities, or those who need immediate mechanical ventilation cannot take part. If eligible, participants will undergo tests that measure their respiratory function and how well non-invasive support is helping them. This research is important as it could lead to better treatment strategies for patients with serious breathing issues.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age \>18 years
- • Acute hypoxic respiratory failure (P/F \< 200)
- Exclusion Criteria:
- • Acute pulmonary edema
- • Chest wall deformities
- • Immediate need for Mechanical Ventilation
- • Pregnancy
- • Hypercapnic RF
About University Of Modena And Reggio Emilia
The University of Modena and Reggio Emilia, a prestigious institution located in Italy, is renowned for its commitment to advancing medical research and education. With a strong focus on innovation and interdisciplinary collaboration, the university plays a pivotal role in conducting clinical trials that aim to improve healthcare outcomes. Its dedicated team of researchers and clinicians are engaged in cutting-edge studies across various medical fields, fostering an environment that encourages scientific inquiry and the translation of research findings into clinical practice. The university's robust infrastructure and emphasis on ethical standards ensure the integrity and reliability of its clinical trials, contributing significantly to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Modena, , Italy
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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