Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop

Launched by LAVAL UNIVERSITY · Feb 7, 2019

Keywords

ClinConnect Summary

The FreeO2 HypHop clinical trial is studying whether a new device, called FreeO2, can automatically adjust the amount of oxygen given to patients experiencing a flare-up of chronic obstructive pulmonary disease (COPD). The goal is to see if using this device can help patients leave the hospital sooner compared to the traditional method of adjusting oxygen levels by hand. This trial is currently looking for participants aged 65 to 74 who have a history of COPD and are experiencing increased breathing difficulties.

To be eligible for the study, participants should have been diagnosed with COPD or suspected COPD, and they need to show signs of a recent worsening in their symptoms, such as more trouble breathing or changes in their sputum (the mucus they cough up). Patients who are interested should know that they will be monitored closely during the trial and will have their oxygen levels adjusted automatically or manually, depending on which group they are placed in. This trial aims to improve care for COPD patients, so if you or someone you know fits the criteria, it might be worth considering participation.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • COPD or suspected COPD ( Age\>40, active or smoking history \> 10pack/years), -
• • Acute exacerbation (increasing dyspnea recently)
• • One or more of the following criteria: increased sputum, modification of sputum purulence,increased dyspnea,
• • Moderate oxygen therapy: Oxygen flow \< 8 lpm (or FiO2 \< 0.60) to maintain a SpO2 \>or = 92% (for long term oxygen therapy, the oxygen flow must be greater than baseline flow to maintain SpO2 \> or = 92%)
• Exclusion Criteria:
• • Patient refusal
• • COPD exacerbation with diagnosis highly related to pulmonary embolism, cardiac pulmonary edema, pneumothorax or sedative overdose
• • No SpO2 signal
• • Encephalopathy score \> 2
• • Delirium
• • Other respiratory support needed (intubation or NIV)
• • Patient on withdrawal life support
• • Advance neoplasia (palliative stage) or terminal respiratory distress
• • Unavailability of FreeO2 device at the randomisation
• • Non optimal patient collaboration