Markers of Trajectory in Pediatric CRPS

Launched by CHILDREN'S HOSPITAL MEDICAL CENTER, CINCINNATI · Feb 8, 2019

Keywords

ClinConnect Summary

This clinical trial, called "Markers of Trajectory in Pediatric CRPS," is focused on understanding Complex Regional Pain Syndrome (CRPS) in children aged 10 to 17. CRPS is a painful condition that can affect recovery due to both brain changes and psychosocial factors, like emotional and social influences. The goal of this study is to identify which of these factors can predict how well children recover from CRPS. Researchers will compare children with CRPS who are receiving treatment to healthy peers, to see how their experiences differ.

To participate, children must be between 10 and 17 years old, fluent in English, and diagnosed with CRPS. They will undergo three sessions over time, including brain imaging and questionnaires about their feelings and experiences. Each session lasts about three hours, and their parents will also provide information. This study is currently recruiting participants, so if you think your child might qualify, it could be an opportunity to help researchers learn more about CRPS and improve treatment outcomes for kids facing this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• All Children:
• • Age between 10 and 17 years old
• • Fluent in English
• Inpatients:
• • Diagnosis of CRPS
• • Former unsuccessful treatment for CRPS
• • Scheduled for or beginning the usual inpatient treatment for CRPS at the FIRST clinic at CCHMC.
• Outpatients:
• • Diagnosis of CRPS
• • Scheduled for or beginning the usual outpatient treatment for CRPS at the pain management clinic
• Healthy children:
• • - No diagnosis of chronic pain.
• Parents:
• • Fluent in English
• • Child participating in the study
• Exclusion Criteria:
• All child participants:
• • Weight/size incompatible with MRI scanner
• • Identification of brain, neurologic, or severe psychiatric abnormalities beyond those normally associated with chronic pain.
• • Documented developmental delays or impairment
• • Any MRI contra-indication, including
• • Braces, stents, clips, pace-maker or other metal implants affecting the safety of the participants in the scanner and/or the quality of the images
• • pregnancy
• • claustrophobia