Study of Cerebral Venous System in Acute Ischemic Stroke Patients Receiving Reperfusion Therapy

Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Feb 11, 2019

Keywords

ClinConnect Summary

The VAST study is researching how the veins in the brain affect recovery in patients who have had an acute ischemic stroke (AIS) and are receiving treatment to restore blood flow, known as reperfusion therapy. In this study, eligible participants must have their stroke symptoms start within the last 24 hours and must receive specific brain imaging tests before and after their treatment. The researchers will look at several key factors, such as the amount of damaged brain tissue and the health of the brain's venous system, which includes important veins that help drain blood from the brain.

To participate in this study, individuals should be between the ages of 65 and 74 and must agree to undergo the necessary imaging tests. It's important to note that anyone who cannot safely receive contrast agents for imaging or who does not provide informed consent will not be eligible. Participants can expect a thorough neurological examination and detailed brain imaging during the study, which will help researchers understand the role of the brain's venous system in recovery and how it relates to potential complications from the treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. receive reperfusion therapy within 24 hours after onset;
• • 2. undergo multimodal magnetic resonance computed tomography before reperfusion therapy and CTP or magnetic resonance perfusion at 24 hours after reperfusion therapy;
• Exclusion Criteria:
• • 1. Contraindication to imaging with contrast agents;
• • 2. Without provision of informed consent.