Dose Effect of Tranexamic Acid on the Incidence of Deep Venous Thrombus in Cardiac Surgery
Launched by SHI JIA · Feb 9, 2019
Trial Information
Current as of August 02, 2025
Unknown status
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients receiving selective cardiac surgery with cardiopulmonary bypass due to coronary, valvular or congenital heart disease
- • Written consent obtained
- Exclusion Criteria:
- • Allergy or contraindication to tranexamic acid
- • Severe renal impairment (serum creatinine \>250 μmol/l, or estimated creatinine clearance \<25 ml/min)
- • Thromboembolic disease including but not limited to: history of pulmonary embolism, spontaneous arterial thrombosis or familial hypercoaguability (eg. Lupus anticoagulant, protein C deficiency)
- • Thrombocytopenia defined as a platelet count \<100,000/ml
- • Coagulopathy defined as an international normalized ratio \> 1.5 prior to surgery
- • Currently enrolled in another perioperative interventional study
- • Pregnancy or lactation
About Shi Jia
Shi Jia is a leading clinical trial sponsor dedicated to advancing medical research and improving patient outcomes through innovative therapeutic solutions. With a focus on rigorous scientific methodologies and ethical standards, Shi Jia collaborates with healthcare professionals, researchers, and regulatory bodies to design and conduct high-quality clinical trials across various therapeutic areas. The organization is committed to transparency, data integrity, and the timely dissemination of results, ensuring that its contributions to the medical community foster advancements in healthcare and enhance the quality of life for patients worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Beijing, , China
Patients applied
Trial Officials
Jia Shi, M.D.
Principal Investigator
Chinese Academy of Medical Sciences, Fuwai Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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