Plaque Calcium Characterization and Ruptured Plaques

Launched by LI MIN · Feb 20, 2019

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technique called ultrashort echo time (UTE) MRI, which helps doctors see and measure calcium buildup in the arteries, particularly in patients with vulnerable plaques that may lead to serious heart problems. The researchers want to find out if this advanced imaging can help identify patients who are at higher risk for complications and if it can distinguish between those who have symptoms and those who do not.

To participate in the study, individuals must be scheduled for a procedure to clear blocked carotid arteries, either through surgery or a stent. However, people with certain conditions, such as having metal implants like pacemakers or experiencing severe anxiety in confined spaces, cannot join. Participants will undergo UTE MRI scans, which are non-invasive and aim to provide valuable information about their arterial health. This research could lead to better ways to predict and manage heart disease in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients referred for carotid endarterectomy or stent were prospectively enrolled.
• Exclusion Criteria:
• • Patients with ferromagnetic metal, active implants such as pacemakers, aneurysm clips, known claustrophobia, and those who were unable to provide informed consent were excluded from enrollment.