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Search / Trial NCT03857490

Heat Therapy in Older Hypertensive Women

Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Feb 25, 2019

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

Ambulatory Blood Pressure Monitoring Sympathetic Neural Control Vascular Function

ClinConnect Summary

This clinical trial is studying the effects of heat therapy on lowering blood pressure in older women with high blood pressure, known as hypertension. Researchers want to find out if soaking the lower legs in warm water can help reduce blood pressure even more effectively when combined with standard blood pressure medications. The trial will involve women aged 65 to 85 who have mild to moderate hypertension. Participants will be divided into two groups: one will receive heat therapy, while the other will immerse their legs in cool water for comparison.

To be eligible for this study, women must have a specific range of blood pressure and be able to understand and speak English. However, those with certain health issues, such as severe hypertension or chronic diseases, will not be able to participate for safety reasons. Participants can expect to engage in the heat therapy for 45 minutes, four times a week, over eight weeks. The study aims to gather information that could eventually lead to new recommendations for managing high blood pressure in older women, making it easier to control and improve their overall health.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Women between the ages of 65-85 years with essential hypertension (systolic BP 140-179 and/or diastolic BP 90-109 mmHg)
  • Must be able to understand and speak English
  • Exclusion Criteria:
  • Illness or disabilities that preclude home-based heat therapy
  • Any evidence of cardiopulmonary disease
  • Severe hypertension (BP ≥180/110 mmHg; for safety reasons)
  • Secondary hypertension
  • Being on ≥3 antihypertensive agents
  • Chronic kidney disease
  • Diabetes mellitus or other systemic illness
  • Any history of substance abuse (other than tobacco)
  • Current cigarette smokers
  • History of gouty arthritis
  • Taking hormonal replacement therapy
  • Being obese (body mass index ≥30 kg/m2)
  • Endurance trained athletes
  • Impaired cognitive function or diagnosed dementia

About University Of Texas Southwestern Medical Center

The University of Texas Southwestern Medical Center is a leading academic medical institution dedicated to advancing healthcare through innovative research, education, and clinical excellence. With a strong emphasis on translational medicine, the center conducts cutting-edge clinical trials aimed at developing novel therapies and improving patient outcomes across a wide range of diseases. Its multidisciplinary approach leverages a collaborative network of renowned faculty, state-of-the-art facilities, and a commitment to ethical research practices, positioning UT Southwestern at the forefront of medical discovery and patient care.

Locations

Dallas, Texas, United States

Patients applied

0 patients applied

Trial Officials

Qi Fu, MD, PhD

Principal Investigator

University of Texas Southwestern Medical Center

Steven Romero, PhD

Principal Investigator

University of North Texas Health Science Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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