Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

Launched by VIVEK JAIN · Feb 28, 2019

Keywords

ClinConnect Summary

This clinical trial is looking at the effects of a nasal spray containing oxytocin on patients with obstructive sleep apnea (OSA) who use a Continuous Positive Airway Pressure (CPAP) machine while sleeping. The goal is to see if the oxytocin spray can help reduce the pressure needed from the CPAP machine, which may help lessen some problems caused by low oxygen levels during sleep.

To participate in this study, individuals must be at least 18 years old and willing to use the CPAP machine. Unfortunately, those with other sleep disorders, pregnant or breastfeeding women, and individuals who cannot provide consent due to language barriers or other reasons are not eligible. The study will last for 35 nights, during which participants will spend three nights at the sleep lab at George Washington University. Importantly, there are no costs for joining the study, and participants will not receive any compensation for their involvement.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Men or women 18 years of age or older.
• Exclusion Criteria:
• • subjects not willing to or otherwise unable to use CPAP for treatment of OSA.
• • Presence of other sleep disorders
• • Pregnant or breastfeeding women
• • Women of child-bearing age (WOCBA) not willing or unable to use an accepted method to avoid pregnancy for the entire duration of the study
• • Prisoners or subjects who are involuntarily incarcerated
• • Subjects who are compulsorily detain or treatment of either a psychiatric or physical (i.e. infectious disease) illness
• • Patients unable to give consent because of a language barrier, or other reason.