Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

Launched by DUFRESNE, CRAIG, MD, PC · Mar 12, 2019

Keywords

ClinConnect Summary

This clinical trial is looking into a treatment called free dermal fat autografting for patients with complex wounds on the head and face. These are wounds that have not healed properly despite standard treatments. The researchers want to see how well this type of graft, which involves taking fat from the patient’s own body and using it to help heal the wound, works over time. To participate, patients need to have a severe wound that has not responded to previous treatments, and they must have had at least two failed attempts to fix the wound or treat any infections.

If someone qualifies for this study, they will have had the grafting procedure done within the last week. During the trial, their healing progress will be monitored for up to two years, which will involve taking photographs and small samples of the grafted area. This trial is important because it aims to find better ways to help patients with challenging wounds heal effectively. Participants will need to be able to understand and consent to the study, and they must speak English.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Presence of a complex craniofacial wound, defined by failure of initial reconstructive and antibiotic treatment and the presence of chronic infection, exposed hardware, irradiated local tissue, or soft tissue volume loss
• • Presence of wound contracture, breakdown of overlying tissue, or challenging anatomical deformities
• • Patient has had two or more failed reconstructive attempts or has failed two or more attempts to treat local infection
• • Speak, read, and understand English
• • Willing to freely give consent
• • Is able or has a legal representative to give consent
• Exclusion Criteria:
• • Absence of a complex craniofacial wound, defined by failure of initial reconstructive and antibiotic treatment and the presence of chronic infection, exposed hardware, irradiated local tissue, or soft tissue volume loss
• • Absence of wound contracture, breakdown of overlying tissue, or challenging aesthetic deformities
• • Patient has not had two or more failed reconstructive attempts or has not failed two or more attempts to treat local infection
• • Does not speak, read, or understand English
• • Unwilling to freely give consent
• • Is unable or does not have a legal representative to give consent