French Registry for Monitoring Pregnancies for Multiple Sclerosis

Launched by HOSPICES CIVILS DE LYON · Apr 1, 2019

Keywords

ClinConnect Summary

This clinical trial, called the French Registry for Monitoring Pregnancies for Multiple Sclerosis, is looking at how pregnancy affects women with multiple sclerosis (MS) and related conditions. The goal is to gather more information about how pregnancy, breastfeeding, and the use of medications during this time can impact both mothers and their babies. By doing this, the researchers hope to provide better guidance to women with MS who are planning to become mothers.

If you have been diagnosed with MS, neuromyelitis optica, or other related disorders, you may be eligible to participate in this study. There are no age limits, and pregnant women can join at any time during their pregnancy. To participate, you need to be able to understand and read French, and give your consent. As a participant, you can expect to share information about your health and pregnancy, which will help healthcare providers understand how to better support women like you during pregnancy. This study is important for improving care for pregnant women with MS and ensuring the best outcomes for both mothers and their children.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * All groups of patients eligible to participate to the Observatoire Français de la Sclérose en Plaque (OFSEP), including :
• • Definite Multiple sclerosis (MS) according to McDonald criteria
• • Whatever the clinical course (single attack MS, relapsing-remitting MS, secondary progressive MS, primary progressive MS)
• • Radiologically Isolated Syndromes (RIS) (will be validated by the RIS expert group)
• • Clinically Isolated Syndromes (CIS)
• • Neuromyelitis optica (NMO) and NMO spectrum disorders (will be validated by the "Neuro-optico-myélite aiguë de Devic et des syndromes neurologiques apparentés" (NOMADMUS) expert group)
• • No age limit (patients under the age of 18 might be included, provided informed consent is obtained from the parents)
• • Ongoing pregnancy: there will be no limit in the gestational age at inclusion. Women can be included at any time before delivery, but the gestational age at inclusion will be recorded and introduced in the analyses whenever pertinent. However, neurologists and patients will be encouraged to start the study as soon as pregnancy is diagnosed.
• • Able to give informed consent
• • Able to read and/or understand French
• Exclusion Criteria:
• • None