Effect of Prednisolone Treatment on Uterine Natural Killer Cells

Launched by CHINESE UNIVERSITY OF HONG KONG · Apr 3, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how a medication called prednisolone might help women who have experienced three or more miscarriages in a row. The researchers want to learn about specific immune cells in the uterus, known as uterine natural killer (uNK) cells, to see how they relate to these miscarriages and the treatment with prednisolone. This study is currently looking for women under 40 years old who have a history of recurrent miscarriages, but there are some health conditions that would prevent someone from participating, such as allergies to the medication or certain uterine and blood disorders.

If you qualify and decide to participate, you'll be part of a study that aims to understand better how this treatment works. Participants can expect to undergo some assessments related to their health history and may receive the medication during the trial. It's important to remember that this is a research study, so the goal is to gather information that could help improve care for women facing similar challenges in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Women with a history of 3 or more consecutive miscarriages
• • 2. Women younger than 40 years old
• Exclusion Criteria:
• • 1. Allergy to prednisolone
• • 2. Women who have any uterine anomaly
• • 3. Antiphospholipid syndrome
• • 4. Hydrosalpinx
• • 5. Thrombophilia
• • 6. Abnormal thyroid function tests
• • 7. women with diabetes,